Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease.
نویسندگان
چکیده
OBJECTIVE To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life. METHODS Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression. RESULTS Analysis of data from 1207 MS patients and 1207 control subjects did not show any significant variation in the month of birth regarding the prevalence of MS in four latitude bands (0-10; 11-20; 21-30; and 31-40 degrees). There was no relationship between the month of birth and the severity of disease in each latitude band. CONCLUSION The results from this study show that MS patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes.
منابع مشابه
Multiple sclerosis in the Southern and Northern hemispheres: the month of birth at different latitudes has the same influence on the prevalence and progression of the disease in the Northern and Southern hemispheres?
The etiopathogenesis of multiple sclerosis (MS) remains unclear in spite of the several attempts to predict the risk of acquiring the disease. Genetic and environmental factors related to disease susceptibility, suggested by many recent studies that configured a multifactorial etiology to MS, reflect its geographical distribution and changes in risk with migration. The incidence of MS seems to ...
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 71 9A شماره
صفحات -
تاریخ انتشار 2013